TY - JOUR AU - Ding, Yunchuan AU - Ortelli, Federica AU - Rossiter, Louise C. AU - Hemingway, Janet AU - Ranson, Hilary PY - 2003 DA - 2003/08/13 TI - The Anopheles gambiae glutathione transferase supergene family: annotation, phylogeny and expression profiles JO - BMC Genomics SP - 35 VL - 4 IS - 1 AB - Twenty-eight genes putatively encoding cytosolic glutathione transferases have been identified in the Anopheles gambiae genome. We manually annotated these genes and then confirmed the annotation by sequencing of A. gambiae cDNAs. Phylogenetic analysis with the 37 putative GST genes from Drosophila and representative GSTs from other taxa was undertaken to develop a nomenclature for insect GSTs. The epsilon class of insect GSTs has previously been implicated in conferring insecticide resistance in several insect species. We compared the expression level of all members of this GST class in two strains of A. gambiae to determine whether epsilon GST expression is correlated with insecticide resistance status. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-4-35 DO - 10.1186/1471-2164-4-35 ID - Ding2003 ER -