Table 1 Comparison of DRIM gene expression and the genetic and phenotypic characteristics of a panel of human breast tumor cell lines
Breast tumor cell line | Metastatic phenotype | Ref. | Estrogen receptor status | Karyotype | Genomic copies of the DRIM gene | Relative DRIM mRNA expression (qPCR) |
|---|---|---|---|---|---|---|
NM2C5 | non-metastatic | (-) | 2N+ | 3 | 100% | |
M4A4 | metastatic | (-) | 2N+ | 2 | 56% | |
T47-D | non-metastatic | (+) | 3N- | 4 | 25% | |
SK-BR-3 | non-metastatic | [17] | (+) | 4N± | 4 | 23% |
MCF-7 | non-metastatic | [20] | (+) | 4N± | 4 | 23% |
MDA-MB-231 | metastatic | (-) | 3N± | 3 | 16% | |
ZR75-1 | non-metastatic | [18] | (+) | 3N± | 3 | 13% |
MDA-MB-468 | metastatic | [13] | (-) | 3N- | 2 | 8% |