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Figure 4 | BMC Genomics

Figure 4

From: Expression of alternatively spliced isoforms of human Sp7 in osteoblast-like cells

Figure 4

Dendrogram showing the relatedness of human Sp7 protein, HsSp7, to other Sp7 proteins from different species and to other members of the human Sp protein family. The predicted relationships were obtained using the Clustal algorithm and drawn using Treeview. The species are: Homo sapiens, Hs; Mus musculus, Mm; Rattus norvegicus, Rn; The proteins and their length and accession numbers are: Sp1 (785 aa, sp_P08047); Sp2 (613 aa, gb_AAA36629); Sp3 (713 aa, gb_AAL58086); Sp4 (784 aa, NP_003103); Sp5, (398 aa, EST contigious sequence homologous to mouse Sp5, NP_071880); Sp6 (376 aa, translation of gb_AK127707). The tree was rooted with a more distant member of the Sp/Krueppel-like factor family, the human TGF-beta inducible early protein, TGF-β-IEG (480 aa, AAC50340) as an out-group. The three Sp7 proteins are most closely related to Sp6.

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