Table 1 Characteristics of the most prominent genes affected by aRNA degradation. Compilation of genes, that are significantly (p < 0.05) subjected to aRNA degradation when 4 hour incubations are compared to 16 hour (n = 3). Table lists the name of the transcripts, descending in the order of the degradation ratio, GenBank accession numbers, transcript size and p-values of the penalized t-statistic as described in [26]. (p. only partial cDNA sequences available at GenBank).

dynein-like protein 10

47 ± 21%

D26502

354 p.

0.0144

integrin beta-1 subunit

12.5 ± 27%

NM_017022

2894

0.0234

tcr delta

11.1 ± 17%

AF259789

359 p.

0.0095

rat hypoxanthine-guanine phosphoribosyltransferase 8.3 ± 32%

S79292

853

0.0325

cd44 protein

8.1 ± 23%

U96138

4038

0.0172

lyn protein non-receptor kinase

6.7 ± 21%

NM_030857

3438

0.0141

cyclic nucleotide phosphodiesterase

5.1 ± 19%

NM_022710

1831

0.0188

tuberin-like protein

5.0 ± 24%

NM_020083

4258

0.0187

2'5' oligoadenylate synthetase-2

4.8 ± 29%

AF068268

2371

0.0269

dopamine d2 receptor rgb-2

4.3 ± 15%

NM_012547

2750

0.0074

rolipram-insensitive phosphodiesterase type 7

4.2 ± 17%

U77880

2870

0.0095

mip protein 261

4.0 ± 22%

X53052

936 p.

0.0158

rin1

3.7 ± 32%

U80076

2548

0.0325

mitogen activated protein kinase kinase kinase

3.7 ± 21%

NM_013055

3754

0.0212

immunoglobulin kappa-chain igkv

3.4 ± 29%

L07406

381 p.

0.0269

rat heart-derived proto-oncogene

3.3 ± 17%

NM_012784

7902

0.0091

rab27b, member ras oncogene family rab27b

3.2 ± 27%

NM_053459

890

0.0234

steroid sensitive gene-1 protein

3.1 ± 31%

NM_022543

3719

0.0306

matrix metalloproteinase 24

3.1 ± 21%

NM_031757

4245

0.0104

flotillin 2

3.0 ± 26%

NM_031830

2629

0.0218

calcium-independent alpha-latrotoxin receptor

3.0 ± 25%

NM_022962

5579

0.0202

neurotrypsin nt

2.9 ± 28%

AJ311671

2499 p.

0.0252

tenascin

2.9 ± 22%

U09361

1727 p.

0.0151

rev-erba-alpha protein

2.9 ± 13%

M25804

2297

0.0056