Figure 2

Metaphase (c,j) and interphase (a,b,d-i,k,l) FISH analysis determines order and relative orientation of selected cancer-related gene probes within 10q24 (m). For interphase figures (a-l), locus identities are indicated in text beneath each representative image, with text color corresponding to the FISH detection color used. Observed frequencies (%) of the probe orders shown are also indicated. Note that the triangular pattern of probes visible on one homologue in a) was classified ambiguous.