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Table 2 Characteristics of subjects

From: Functional classes of bronchial mucosa genes that are differentially expressed in asthma

Control subjects

Age

Sex

FVC* 1(%)

FEV1* 1(%)

PC20 mg/ml †

Allergy‡

(1) 21

F

3.33 (97)

2.73 (91)

70.9

None

(2) 20

M

6.02 (107)

5.10 (105)

>128

None

(3) 20

M

5.52 (98)

4.43 (101)

53.3

None

(4) 29

F

2.84 (80)

2.59 (86)

61.1

None

Asthmatic subjects

(1) 21

F

3.60 (91)

3.25 (96)

6.12

C, D, DPt, Du, G, Rw, T

(2) 20

F

3.50 (99)

2.80 (90)

2.53

C, D, DPt, G, Du, Rw, T

(3) 23

F

3.84 (100)

3.07 (96)

1.01

C, D, G, DPt, T

(4) 39

F

3.96 (112)

3.21 (110)

2.23

C, Du, G, Rw, T

  1. * Forced vital capacity (FVC) and pre-bronchodilator forced expiratory volume in one second (FEV1) expressed in liter and (%) of predicted. † Concentration of methacholine inducing a 20% fall in FEV1. ‡ Skin response read at 10 min if mean wheal diameter ≥ 3 mm; C: cat, D: dog, DPt: D. Pteronyssinus, Du: dust, G: grass pollens, M: mold, Rw: ragweed, T: tree pollens. A wheal response to histamine ≥ 3 mm served as a positive control.