The MME flanked by two hypothetical genes. This MME contains an intergenic sequence in N. gonorrhoeae strain FA1090 , and a hypothetical gene in N. meningitidis strain Z2491 . In N. gonorrhoeae strain FA19 (AY386271) there is a homologue of the meningococcal CDS, which has been disrupted by a CREE 44 bp into the gene. The CREE in this location introduces a termination codon and generates a frame-shift. However, it also generates a potential promoter 5' of a potential ribosomal binding site and secondary initiation codon internal to NMA2121. This is the point of a chromosomal rearrangement in N. meningitidis strains MC58  and FAM18. Similar genes are indicated in the same colour.