A nucleotide-level alignment of ELN in multiple species displaying variable structure in the coding regions, as aligned by PipMaker. The upper panel shows the alteration of a 5' splice junction due to a gap in the human sequence, indicating that some changes in the ELN gene are recent. The lower panel shows gaps in all sequences except one, which would normally indicate an insertion in that one sequence. However, the gaps differ in size (and are thus likely a product of multiple different events), suggesting that the region is indeed undergoing dynamic rearrangements. Panels A and B are from the same alignment, however differences result from exons that do not align in different species.