TY - JOUR AU - Fukuoka, Yutaka AU - Inaoka, Hidenori AU - Kohane, Isaac S. PY - 2004 DA - 2004/01/13 TI - Inter-species differences of co-expression of neighboring genes in eukaryotic genomes JO - BMC Genomics SP - 4 VL - 5 IS - 1 AB - There is increasing evidence that gene order within the eukaryotic genome is not random. In yeast and worm, adjacent or neighboring genes tend to be co-expressed. Clustering of co-expressed genes has been found in humans, worm and fruit flies. However, in mice and rats, an effect of chromosomal distance (CD) on co-expression has not been investigated yet. Also, no cross-species comparison has been made so far. We analyzed the effect of CD as well as normalized distance (ND) using expression data in six eukaryotic species: yeast, fruit fly, worm, rat, mouse and human. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-5-4 DO - 10.1186/1471-2164-5-4 ID - Fukuoka2004 ER -