Chromosomal localization. (A) Localization of the Spatial probe on WMP murine metaphase: R-banded chromosomes are red-stained with propidium iodide. The FITC fluorescent signals (green), corresponding to Spatial gene, are located on chromosome 10 and belong to the robertsonian translocation Rb(10; 17). (B) On the left, the map of mouse chromosome 10 zooming on B3-B4 bands where are localized 2 translocation points, and on the right, 2 human syntenic regions located on Ch6 and Ch10. (C) The repartition of genes within B3 to B5.3 bands on mouse chromosome 10.