Figure 4
From: Characterization of the GATC regulatory network in E. coli
Comparison of the distribution of the "GATC genes" with the "Mitomycin C genes". The genes of E. coli have been classified according to the 15 classes used by EcoCyc. In this figure we compare the distribution of the genes containing a GATC cluster ("GATC genes") with the genes whose expression is sensitive to the stress caused by the antibiotic mitomycin C (genes involved in the SOS response and other stress response pathways) according to the recent transcriptome analysis carried out by [13] ("Mitomycin C genes"). (See Table 2 for the corresponding numerical data.) The distributions are different (p-value = 2 × 10-6): the "GATC genes" contain a much smaller proportion genes involved in "Translation", whilst the groups "Fatty acid/ Phospholipid metabolism", "Nucleotide metabolism" and "Energy metabolism" are overrepresented.