Table 1 Studies identifying adult mammalian retina / RPE transcripts and details on gene data retrieval
Reference | Source / method a) | Species b) | Original dataset | No. of genes retrieved c) (non-redundant) | No. of genes identified in ≥ 2 studies |
|---|---|---|---|---|---|
In-silico projects | |||||
[20] | Retina, TIGR (ID: version 3.3) | Hs | 1,047 | 30 | 30 |
[19] | Retina, TIGR (ID: version 3.3) | Hs | 1,315 | 11 | 11 |
[21] | Retina, UniGene (ID: build 118) | Hs | 4,974 | 1,485 | 1,480 |
[22] | Retina, UniGene (ID: build 113) | Hs | 6,190 | 46 | 45 |
[23] | Retina, EST (dbEST) | Hs | 40,000 | 117 | 110 |
UniGene (Build 162) d) | Retina | Hs | 3,560 | 1,612 | 1,211 |
UniGene (Build 162) d) | RPE | Hs | 1,760 | 1,506 | 1,116 |
UniGene (Build 162) d) | Retina & RPE | Hs | 11,976 | 9,178 | 9,178 |
cDNA library sequencing | |||||
[24] | Fovea, conventional | Hs | 209 | 40 | 38 |
[25] | Retina, conventional | Hs | 607 | 475 | 465 |
[37] | Retina & RPE, SSH | Hs | 401 | 6 | 6 |
[30] | Retina, subtracted | Hs | 137 | 49 | 48 |
[31] | Retina, PC and subtracted | Cf | 173 | 66 | 65 |
[26] | RPE, primary and amplified, conventional | Hs | 2,101 | 336 | 330 |
[38] | RPE, SSH | Bt | 1,000 | 35 | 34 |
[27] and online e) | Retina, PC | Hs | 2,701 | 2,096 | 2,059 |
[28] and online f) | RPE, PC | Hs | 6,182 | 3,657 | 3,608 |
[29] | Retina, PC (ID: MRA) | Mm | 1,793 | 421 | 412 |
[39] | Retina, SSH | Hs | 1,080 | 310 | 301 |
[39] | RPE, SSH | Bt | 2,350 | 343 | 329 |
Microarray Analysis | |||||
[32] | Retina, Affymetrix (ID: Mu11K subB) | Mm | 6,540 | 67 | 67 |
[33] | Retina, custom array | Hs | 10,034 | 530 | 508 |
Serial Analysis of Gene Expression | |||||
[34] | Retina, adult | Mm | 54,009 | 4,233 | 3,974 |
[35] | Retina (ID: HMAC2) | Hs | 102,359 | 7,269 | 6,919 |
[35] | Retina (ID: HPR1) | Hs | 59,661 | 5,689 | 5,512 |
[35] | Retina (ID: HPR2) | Hs | 105,312 | 7,268 | 6,955 |
[35] | RPE (ID: HRPE1) | Hs | 53,666 | 5,755 | 5,211 |
Total (with inter-study redundancy) | 52,630 | 50,022 | |||
Total (without redundancy) | 15,645 | 13,037 |