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Table 2 Expression of IGFBP3 and RXRalpha in Prostatic Epithelium

From: Cross-species global and subset gene expression profiling identifies genes involved in prostate cancer response to selenium

  Normal Prostate Nodular Hyperplasia HGPIN Prostate Cancer Metastatic Cancer
IGFBP3      
Positive cases 105 62 49 202 25
Negative cases 5 1 9 36 8
Statistics (comparison)   p = 0.0036 (cancer) N.S. (cancer) p = 0.0044 (normal) N.S. (cancer)
IGFBP3      
Intensity (avg+/-std) 2.47 +/- 0.70 2.49 +/- 0.65 2.57 +/- 0.82 2.74 +/- 0.56 2.79 +/- 0.49
Percentage cells (avg+/- std) 8.3 +/- 13.5 7.5 +/- 12.5 8.8 +/- 15.2 4.4 +/- 6.6 8.5 +/- 12.6
Nuclear cases 92 59 40 94 8
Cytoplasmic cases 22 6 18 152 11
Statistics (comparison)   p < 0.00001 (cancer) p = 0.065 (cancer) p < 0.00001 (normal) N.S. (cancer)
RXRalpha      
Positive cases 92 58 35 112 16
Negative cases 10 3 31 125 19
Statistics (comparison)   p < 0.00001 (cancer) N.S. (cancer) p < 0.00001 (normal) N.S. (cancer)
RXRalpha      
Intensity (avg+/-std) 2.73 +/- 0.51 2.78 +/- 0.50 2.83 +/- 0.38 2.76 +/- 0.49 3 +/- 0
Percentage cells (avg+/- std) 20.0 +/- 25.5 23.2 +/- 25.7 8.4 +/- 12.5 8.6 +/- 12.6 4.2 +/- 4.6
Nuclear cases 92 58 35 107 16
Cytoplasmic cases 2 0 6 9 0
Statistics (comparison)   N.S. (cancer) N.S. (cancer) N.S. (normal) N.S. (cancer)
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