Combined analysis of expression data and transcription factor binding sites in the yeast genome

BMC Genomics

Table 4 Potential a 1-α 2 Target Sites in the Promoters of Non-Haploid-specific Genes

ORF	Gene	Expression^a p-val	Binding p-val	Combined p-val	a1-α 2 ChIP^b
YGL191W	COX13	0.4111	0.0053	0.0021	+
YPL099C	FMP14	0.1622	0.0075	0.0012
YLR059C	REX2	0.1532	0.0098	0.0015	+/-
YDR212W	TCP1	0.5694	0.0017	0.0010
YJL124C	LSM1	0.0830	0.0120	0.0010	+/-
YAR033W	MST28	0.7419	0.0133	0.0099	-
YMR015C	ERG5	0.6021	0.0138	0.0083	-
YMR291W		0.2659	0.0218	0.0058	-
YPL188W	POS5	0.2648	0.0230	0.0061	+/-
YDR101C	ARX1	0.3694	0.0298	0.0110	+
YHR058C	MED6	0.4507	0.0350	0.0157
YGL117W		0.5577	0.0370	0.0206
YIL027C	KRE27	0.5762	0.0381	0.0220

^a The ranking of haploid-specific gene expression determined by analysis of microarray data [11].
^b A + indicates that the a 1-α 2 binds to the promoter by ChIP assay. A +/- indicates weak (2-fold) enhancement of the band in a/α cells by ChIP assay.

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