Figure 2

Global data characteristics (A) Global correlation of bovine (X-axis) and human (Y-axis) experiments. The plot shows a log-log (base 2) plot of the mean signal intensities from the four independent experiments for each gene. The red line shows the regression line, the box displays the parameters of the regression line (intercept, slope) and the overall correlation. Four genes that are significantly differentially expressed as judged by using the Wilcoxon's rank-sum test are denoted by black diamond shapes. (B) MA-plot of a single experiment. The X-axis show the log (base 2) of the squared product of Cy5-red and Cy3-green intensities of each gene in the same experiment. Y-axis shows the log-ratio (base 2) of red and green intensity. The horizontal lines mark the two-fold over-expressed genes (Top line; bovine over-expression and bottom line; human over-expression). (C). Classification of detection levels of the 349 genes. The genes were sub-divided into three classes of expression levels. Class 1 (BG-tag < 0.8) – low (not detected). Class 2 (BG-tag between 0.8 and 0.9) – medium (boarderline detection) and Class 3 (BG-tag > 0.9) – high expression (readily detectable) The number of genes (X-axis) within each class (Y-axis) is also shown in the figure (black = bovine, white = human).