Figure 2

Gene structure of human Sp8. The human genomic sequences corresponding to the Sp8 cDNAs are located on clones CTA-324D18 and CTB-86D3. The location of a CpG island is shown in green. The first exon encoding the start of the Sp8L transcript is labelled 1a and that of Sp8S, 1b. The ORF is indicated by closed boxes. The sequences around the initiation methionine codons (underlined) are shown with those nucleotides corresponding to Kozak consensus sequence coloured red. The location of the TGA stop codon and a potential polyadenylation signal, AATAAA are also shown. The sizes of the exons and introns, in base pairs, are indicated.