Sequence comparison of the human Sp8 protein with those from other vertebrate species. The species are man, Homo sapiens, Hs; mouse, Mus musculus, Mm; chimpanzee, Pan troglodytes, Pt; rat Rattus norvegicus, Rn and Zebrafish, Danio rerio, Dr. The location of the exon/exon boundaries are underlined in black on the protein sequences. The methionine residues at the start of translation of Sp8S are underlined in red. The positions of the Sp, BTD-box and three zinc-finger domains found in most Sp protein family members are indicated. The conserved residues are shown by (*), strongly conserved residues by (:) and weakly conserved residues by (.). Stop codons are indicated by a hash. Residues are colour coded: basic, DE, blue; acidic,_KR, pink; polar, CGHNQSTY, green and hydrophobic, AFILMPVW, red.