Figure 6
Top seven over-represented functional classes in the meta-signature. Black bars represent proportion of genes associated with each of the GO terms among the meta-signature, and white bars represent the corresponding proportion among the total study population of 2555 genes. P-value represents the significance of over-representation based on a hypergeometric distribution, and is calculated as the probability of observing larger proportion of a particular functional group genes in the meta-signature than in the entire gene set. The meta-signature genes are listed under each functional class.