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Table 3 Comparison of the performances of the individual signatures and the meta-signature in each single study cohort. Table lists odds ratios (95% confidence interval) comparing the odds of actual recurrence for those being classified as high risk to the odds of recurrence for those being classified as low risk of recurrence by each signature.

From: Prognostic meta-signature of breast cancer developed by two-stage mixture modeling of microarray data

  Cohort
Signature Sorlie (n = 58) van't Veer (n = 78) Sotiriou (n = 98) Huang (n = 71)
Sorlie (D = 10) 18.6 (5.0, 69.5) 2.1 (0.8, 5.4) 2.3 (1.0, 5.3) 10.87 (3.5, 33.8)
van't Veer (D = 60) 3.1 (1.1, 9.2) 10.6 (3.3, 33.9) 4.1 (1.7, 9.7) 1.3 (0.5, 3.4)
Sotiriou (D = 100) 1.7 (0.6, 5.0) 3.5 (1.4, 8.9) 7.8 (3.0, 20.1) 1.5 (0.6, 3.7)
Huang (D = 130) 5.1 (1.6, 15.7) 2.3 (0.9, 5.6) 0.9 (0.4, 2.0) 184.9 (30.1, 1137.2)
Meta (D = 90) 25.0 (4.2, 149.0) 4.1 (1.6, 10.6) 6.0 (2.5, 14.5) 5.8 (2.1, 16.5)
  1. D is the number of genes in a signature. n is the sample size for each cohort.