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Table 2 Number of distinct sequences in the Top 10 most common KEGG pathways. The KEGG pathway name and number of distinct sequences (clusters or singletons) from FunnyBase are presented. There are more distinct sequences than enzymes in a pathway because many enzymes have several protein subunits and many proteins have several different loci encoding the same subunit (e.g., NADH dehydrogenase, a protein complex of oxidative phosphorylation, has 26 protein subunits and 42 loci for these subunits).

From: FunnyBase: a systems level functional annotation of Fundulus ESTs for the analysis of gene expression

Sequence count for TOP 10 pathways

Glycolysis/Gluconeogenesis

89

Oxidative phosphorylation

86

Fatty acid metabolism

70

Pyruvate metabolism

69

Tryptophan metabolism

66

Butanoate metabolism

48

Glycerolipid metabolism

47

Valine, leucine and isoleucine degradation

46

Glycine, serine and threonine metabolism

44

Propanoate metabolism

44