Table 1 Over-representation of protein domains in genes flanking UCRs. Bonferroni-corrected and uncorrected Fisher Exact Test p-values are shown for the 16 most over-represented InterPro domains. Typical transcription factor domains (DNA binding domains) are indicated in bold. A full list of all InterPro domains with P-values is given in [Additional file 3].
Domain description | INTERPRO ID | Fisher test P value | Corrected P value |
|---|---|---|---|
HTH_lambrepressr | IPR000047 | 6.40E-20 | 5.36E-17 |
Homeobox | IPR001356 | 1.60E-12 | 1.34E-09 |
Antennapedia | IPR001827 | 1.37E-10 | 1.15E-07 |
Paired_box | IPR001523 | 2.39E-05 | 2.00E-02 |
HLH_basic | IPR001092 | 2.40E-05 | 2.01E-02 |
POU_domain | IPR000327 | 3.06E-05 | 2.56E-02 |
Homeo_OAR | IPR003654 | 3.08E-05 | 2.58E-02 |
TF_Fork_head | IPR001766 | 6.15E-05 | 5.15E-02 |
Znf_C4steroid | IPR001628 | 7.45E-05 | 6.23E-02 |
Hormone_rec_lig | IPR000536 | 1.06E-04 | 8.86E-02 |
HMG_12_box | IPR000910 | 1.81E-04 | 1.51E-01 |
Stdhrmn_receptor | IPR001723 | 2.63E-04 | 2.20E-01 |
COUP_TF | IPR003068 | 7.62E-04 | 6.38E-01 |
LIM | IPR001781 | 1.10E-03 | 9.18E-01 |
RtnoidX_receptor | IPR000003 | 1.28E-03 | 1.07E+00 |
FN_III | IPR003961 | 2.57E-03 | 2.15E+00 |