Phylogenitic tree of the FBG domains from A. gambiae and D. melanogaster . The seed alignment used for constructing the tree was the multiple alignment sequences of representative set of the FBG domains of FREP families in A. gambiae and D. melanogaster. The phylogenetic tree was constructed as described in methods and detailed in Fig. 5. The FBG domains of each FREP are denoted by their gene name in GenBank. The name of the FREP from A. gambiae start with E, and the name of the FREP from D. melanogaster start with A.