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Table 1 List of 30 P. aeruginosa genes most strongly induced and repressed in response to hydrogen peroxide

From: Microarray analysis of Pseudomonas aeruginosa reveals induction of pyocin genes in response to hydrogen peroxide

Gene (Name)

Fold change

p-value

Protein (Function)

Induced Genes

PA5530

24.7

0.008

Probable MFS dicarboxylate transporter (Membrane proteins; Transport of small molecules)

PA1466

13.9

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA2288

10.3

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA3414

9.8

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA4763 (recN)

8.3

0.008

DNA repair protein (DNA replication, recombination, modification and repair)

PA0182

6.8

0.024

Probable short-chain dehydrogenase (Putative enzymes)

PA3008

5.7

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA0670

5.4

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA0612

5.3

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA0641

5.0

0.008

Probable bacteriophage protein (Related to phage, transposon, or plasmid)

PA0671

5.0

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA4613 (katB)

4.5

0.024

Catalase (Adaptation, protection)

PA3413

4.4

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA0620

4.2

0.008

Probable bacteriophage protein (Related to phage, transposon, or plasmid)

PA0615

4.2

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA5471

4.1

0.024

Hypothetical protein (Hypothetical, unclassified, unknown)

PA5470

4.1

0.024

Probable peptide chain release factor (Translation, post-translational modification, degradation)

PA3007 (lexA)

4.0

0.008

Repressor protein (Adaptation, protection; Translation, post-translational modification, degradation)

PA0922

3.7

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA0635

3.6

0.008

Hypothetical protein (Related to phage, transposon, or plasmid)

PA0616

3.5

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA0634

3.5

0.008

Hypothetical protein (Related to phage, transposon, or plasmid)

PA0625

3.4

0.008

Hypothetical protein (Related to phage, transposon, or plasmid)

PA0636

3.4

0.008

Hypothetical protein (Related to phage, transposon, or plasmid)

PA0617

3.4

0.008

Probable bacteriophage protein (Hypothetical, unclassified, unknown)

PA0633

3.3

0.008

Hypothetical protein (Related to phage, transposon, or plasmid)

PA0637

3.3

0.008

Conserved hypothetical protein (Related to phage, transposon, or plasmid)

PA3923

3.3

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA4582

3.2

0.008

Conserved hypothetical protein (Hypothetical, unclassified, unknown)

PA0638

3.2

0.008

Probable bacteriophage protein (Hypothetical, unclassified, unknown)

Repressed Genes

PA2398 (fpvA)

5.7

0.008

Ferripyoverdine receptor (Transport of small molecules)

PA4156

5.1

0.008

Probable TonB-dependent receptor (Transport of small molecules)

PA4230 (pchB)

4.3

0.008

Salicylate biosynthesis protein (Transport of small molecules; Secreted Factors)

PA2405

3.9

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA2409

3.7

0.008

Probable permease of ABC transporter (Membrane proteins; Transport of small molecules)

PA5235 (glpT)

3.4

0.008

Glycerol-3-phosphate transporter (Membrane proteins; Transport of small molecules)

PA4225 (pchF)

3.3

0.008

Pyochelin synthetase (Transport of small molecules; Secreted Factors)

PA2407

3.3

0.008

Probable adhesion protein (Motility & Attachment)

PA2403

3.2

0.008

Hypothetical protein (Hypothetical, unclassified, unknown; Membrane proteins)

PA5479 (gltP)

3.2

0.008

Proton-glutamate symporter (Membrane proteins; Transport of small molecules)

PA3009

3.1

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA2426 (pvdS)

3.0

0.024

Sigma factor (Transcriptional regulators)

PA2404

3.0

0.008

Hypothetical protein (Hypothetical, unclassified, unknown; Membrane proteins)

PA2667

3.0

0.008

Conserved hypothetical protein (Transcriptional regulators)

PA3610 (potD)

3.0

0.008

Polyamine transport protein (Transport of small molecules)

PA4555 (pilY2)

3.0

0.008

Type 4 fimbrial biogenesis protein (Motility & Attachment)

PA1414

2.9

0.024

Hypothetical protein (Hypothetical, unclassified, unknown)

PA0280 (cysA)

2.9

0.024

Sulfate transport protein (Transport of small molecules)

PA2408

2.9

0.008

Probable ATP-binding component of ABC transporter (Transport of small molecules)

PA4839 (speA)

2.9

0.008

Biosynthetic arginine decarboxylase (Amino acid biosynthesis and metabolism)

PA4231 (pchA)

2.9

0.008

Salicylate biosynthesis isochorismate synthase (Secreted Factors; Transport of small molecules)

PA0281 (cysW)

2.8

0.008

Sulfate transport protein (Membrane proteins; Transport of small molecules)

PA1228

2.8

0.008

Hypothetical protein (Hypothetical, unclassified, unknown)

PA5049 (rpmE)

2.8

0.008

50S ribosomal protein (Translation, post-translational modification, degradation)

PA2619 (infA)

2.7

0.008

Initiation factor (Translation, post-translational modification, degradation)

PA4221 (fptA)

2.7

0.008

Fe(III)-pyochelin receptor precursor (Transport of small molecules)

PA0976

2.7

0.008

Conserved hypothetical protein (Hypothetical, unclassified, unknown)

PA5446

2.7

0.048

Hypothetical protein (Hypothetical, unclassified, unknown)

PA4229 (pchC)

2.6

0.008

Pyochelin biosynthetic protein (Transport of small molecules; Secreted Factors)

PA4218

2.6

0.008

Probable transporter (Membrane proteins; Transport of small molecules)