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Table 1 Variation in pI in functionally classified groups of COGs. The table lists functional groups of COGs as defined in the COG website [22] along with the results of the Dunn Multiple Comparison test. Ri – mean rank for the group, Rt – mean rank for sample representing the complete distribution. Significant values are those where |Rt - Ri| > 467.35 which is calculated for α = 0.2

From: Comparison of theoretical proteomes: Identification of COGs with conserved and variable pI within the multimodal pI distribution

   R i R i - R t
Metabolism
C Energy production and conversion 2563.72 276.96
E Amino acid transport and metabolism 2792.99 47.69
F Nucleotide transport and metabolism 2191.12 649.56
G Carbohydrate transport and metabolism 2958.98 -118.3
H Coenzyme metabolism 2736.4 104.28
I Lipid metabolism 2587.87 252.81
Q Secondary metabolism biosynthesis, transport and catabolism 2479.07 361.62
Information storage and processing
J Translation, ribosomal structure and biogenesis 3399.31 -558.63
K Transcription 2977.93 -137.25
L DNA replication, recombination and repair 3530.56 -689.88
Cellular process
M Cell Envelope biogenesis, Outer membrane 3287.13 -446.45
N Cell motility and secretion 2722.08 118.6
O Post translation modification, protein turnover, chaperones 2445.01 395.67
P Inorganic ion transport and metabolism 3482.93 -642.25
T Signal transduction mechanisms 2219.23 621.45
D Cell devision and chromosome partitioning 2836.43 4.25
Poorly characterized
R General function prediction only 3189.18 -348.5
S Function unknown 2918.88 -78.2
   Rt = 2840.68