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Table 1 Variation in pI in functionally classified groups of COGs. The table lists functional groups of COGs as defined in the COG website [22] along with the results of the Dunn Multiple Comparison test. Ri – mean rank for the group, Rt – mean rank for sample representing the complete distribution. Significant values are those where |Rt - Ri| > 467.35 which is calculated for α = 0.2

From: Comparison of theoretical proteomes: Identification of COGs with conserved and variable pI within the multimodal pI distribution

  

R i

R i - R t

Metabolism

C

Energy production and conversion

2563.72

276.96

E

Amino acid transport and metabolism

2792.99

47.69

F

Nucleotide transport and metabolism

2191.12

649.56

G

Carbohydrate transport and metabolism

2958.98

-118.3

H

Coenzyme metabolism

2736.4

104.28

I

Lipid metabolism

2587.87

252.81

Q

Secondary metabolism biosynthesis, transport and catabolism

2479.07

361.62

Information storage and processing

J

Translation, ribosomal structure and biogenesis

3399.31

-558.63

K

Transcription

2977.93

-137.25

L

DNA replication, recombination and repair

3530.56

-689.88

Cellular process

M

Cell Envelope biogenesis, Outer membrane

3287.13

-446.45

N

Cell motility and secretion

2722.08

118.6

O

Post translation modification, protein turnover, chaperones

2445.01

395.67

P

Inorganic ion transport and metabolism

3482.93

-642.25

T

Signal transduction mechanisms

2219.23

621.45

D

Cell devision and chromosome partitioning

2836.43

4.25

Poorly characterized

R

General function prediction only

3189.18

-348.5

S

Function unknown

2918.88

-78.2

  

Rt = 2840.68