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Table 2 Top 20 expressed genes in normal cervical tissue.

From: Characterization of the global profile of genes expressed in cervical epithelium by Serial Analysis of Gene Expression (SAGE)

Tag sequence

Tags

TPMa

UniGene ID

Gene

Cluster name

Biological Functionb

TACCTGCAGA

515

16930

Hs.416073

S100A8

S100 calgranulin A

Regulation of cell cycle progression and differentiation.

TAGGTTGTCT

356

11703

Hs.374596

TPT1

Tumor protein, translationally-controlled 1

Unknown

TTTCCTGCTC

276

9073

Hs.139322

SPRR3

Small proline-rich protein 3

Cross-linked envelope protein of keratinocytes

GAGGGAGTTT

201

6607

Hs.523463

RPL27A

Ribosomal protein L27a

Component of the ribosomal 60S subunit

GTGACCACGG

188

6180

Hs.436980

GRIN2C

Glutamate receptor, N-methyl D-aspartate 2C

Ionotropic glutamate receptor

GTGGCCACGG

184

6049

Hs.112405

S100A9

S100 calcium binding protein A9 (calgranulin B)

Regulation of cell cycle progression and differentiation.

GGGCTGGGGT

173

5687

Hs.425125; Hs.90436

RPL29; SPAG7

Ribosomal protein L29; Sperm associated antigen 7

Component of the ribosomal 60S subunit.

GCATAATAGG

168

5523

Hs.381123

RPL21

Ribosomal protein L21

Component of the ribosomal 60S subunit.

TCAGATCTTT

161

5292

Hs.446628

RPS4X

Ribosomal protein S4, X-linked

Component of the ribosomal 40S subunit.

GTTGTGGTTA

155

5095

Hs.99785

 

FLJ21245

Unknown

GGATTTGGCC

151

4964

Hs.437594

RPLP2

Ribosomal protein, large P2

Component of the ribosomal 60S subunit.

TTGGGGTTTC

143

4701

Hs.448738

FTH1

Ferritin, heavy polypeptide 1

Important for iron homeostasis, stores iron in a soluble, nontoxic, readily available form.

TTGGTCCTCT

138

4536

Hs.381172

RPL41

Rribosomal protein L41

Component of the ribosomal 60S subunit.

TGCACGTTTT

130

4273

Hs.265174

RPL32

Ribosomal protein L32

Component of the ribosomal 60S subunit.

ACAAAGCATT

128

4208

Hs.369982

IGFBP5

Insulin-like growth factor binding protein 5

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGF on cell culture.

AGGGCTTCCA

122

4010

Hs.401929

RPL10

Ribosomal protein L10

Component of the ribosomal 60S subunit.

CCACTGCACT

114

3747

Hs.107003

CCNB1IP1

Cyclin B1 interacting protein 1

Functions in progression of the cell cycle through G(2)/M.

GGCAAGCCCC

107

3517

Hs.148340

RPL10A

ribosomal protein L10a

Component of the ribosomal 60S subunit.

CTGGGTTAAT

105

3451

Hs.334534

GNS

Glucosamine (N-acetyl)-6-sulfatase

Lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate.

TGCACTTCAA

103

3386

Hs.62886

SPARCL1

SPARC-like 1 (mast9, hevin)

Calcium ion binding

  1. aTPM: Tags per million; [(Tag frequency)(1000,000)/Total No of sequenced tags].
  2. bBiological function obtained from SOURCE, at http://smd.stanford.edu/cgi-bin/source/sourceSearch