Figure 4
From: A TNF-induced gene expression program under oscillatory NF-κB control
Ingenuity Pathway Analysis of biological pathways controlled by Early and Late genes. (a) Early gene pathway. Shown is a graphical representation of the highest scoring pathway controlled by the genes in Cluster III. Shown are labeled nodes representing individual protein functions and their relationship represented by edges. Nodes are colored by changes in expression, with red indicating > 10 fold change; pink > 2-fold and < = 10-fold change; no color indicating < = 2-fold change or data is not present. Squares indicate cytokines, circles indicate chemokines, and ovals indicate transcription factor. For the edges, an arrow indicates "acts on". Horizontal lines indicate the most likely subcellular location for the protein encoded by each node. See Legend to Table II for the index of relevant abbreviations. (b) Late gene pathway. Graphical representation of the highest scoring pathway controlled by the genes in Cluster III. See Fig. 2A for explanation of figure and symbols.