Table 1 GO Mapping of NF-κB-dependent genes. Affymetrix probe sets were mapped to Gene Ontology (GO) Biological Process and Molecular Function categories [DAVID, Ref [23]]. For each group, the top 5 ranked processes or functions are tabulated with the number of probe sets and the percentage of the dataset (%) that map to the given process or function, and the statistical significance for enrichment (p value).
From: A TNF-induced gene expression program under oscillatory NF-κB control
Early | Middle | ||||||
|---|---|---|---|---|---|---|---|
Molecular Function | Num | % | p Value | Molecular Function | Num | % | p Value |
CYTOKINE ACTIVITY | 6 | 31.6 | 1.44E-06 | PROTEIN BINDING | 5.000 | 29.400 | 0.048 |
RECEPTOR BINDING | 7 | 36.8 | 8.1E-06 | SUGAR BINDING | 2.000 | 11.800 | 0.092 |
CHEMOKINE ACTIVITY | 4 | 21.1 | 1.37E-05 | CARBOHYDRATE BINDING | 2.000 | 11.800 | 0.096 |
CHEMOKINE RECEPTOR BINDING | 4 | 21.1 | 1.37E-05 | ||||
G-PROTEIN-COUPLED RECEPTOR BINDING | 4 | 21.1 | 1.52E-05 | ||||
Late | Paradoxical | ||||||
Molecular Function | Num | % | p Value | Molecular Function | Num | % | p Value |
PEPTIDE TRANSPORTER ACTIVITY | 2 | 12.5 | 0.005 | CTD PHOSPHATASE ACTIVITY | 2.000 | 12.500 | 0.044 |
PRIMARY ACTIVE TRANSPORTER ACTIVITY | 3 | 18.8 | 0.059 | Mg-DEPENDENT Ser/Thre PHOSPHATASE | 2.000 | 12.500 | 0.044 |
PROTEIN BINDING | 5 | 31.3 | 0.063 | MYOSIN PHOSPHATASE ACTIVITY | 2.000 | 12.500 | 0.044 |
PROTEIN PHOSPHATASE TYPE 2B ACTIVITY | 2.000 | 12.500 | 0.044 | ||||
PROTEIN PHOSPHATASE TYPE 2C ACTIVITY | 2.000 | 12.500 | 0.044 | ||||