Figure 2

Chromosomal localizations and exon compositions of the human and mouse pART family members. A) pART family members are sorted by subgroup on the basis of similarities in amino acid sequence, intron positions and associated protein domains. Color-coding of subgroups is as follows: 1 = red, 2 = pink, 3 = orange, 4 = green, 5 = grey. This color-coding is used in subsequent figures. Official gene designations, common aliases and accession numbers are shown. Exon compositions and lengths of open reading frames are given for the longest known or predicted gene transcripts. Available full length cDNAs from the Mammalian Gene Collection (MGC) are indicated with their respective accession numbers. MGC cDNAs which apparently do not contain the full open reading frame are indicated in parentheses. Hs = Homo sapiens, Mm = Mus musculus. B) Chromosomal localizations of pART genes were determined by tBLASTn searches of the respective genome sequences using the amino acid sequences of the catalytic domains of individual pARTs. Members of the five pART family subgroups are color-coded as in A).