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Table 3 Promoter SNPs distribution on predicted transcription factor binding sites. Frequency of SNPs appearing in promoter regions and in putative transcription factor binding sites. The frequency of SNPs is significantly higher in putative binding sites than in the surrounding sequence (p = 2.2 × 10-16).

From: The distribution of SNPs in human gene regulatory regions

Categories SNPs Nucleotides Frequency
Inside a binding site 3,804 1,890,176 0.20%
Outside the binding site 31,054 25,555,824 0.12%
Total 34,858 27,446,000 0.13%