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Table 1 NO-regulated cell cycle related genes

From: cGMP-independent nitric oxide signaling and regulation of the cell cycle

GenBank Symbol Functional category Fold changea
G1/S
J04111 JUN Regulation of cell cycle 3.68 ± 0.76
U09579 CDKN1A (p21) CDK inhibitor 2.06 ± 0.58
U77949 CDC6 DNA replication 1.95 ± 0.48
M74093 CCNE1 Cell cycle control 1.77 ± 0.31
X89398 UNG DNA repair 1.68 ± 0.30
S49592 E2F1 G1 phase of mitotic cell cycle 1.60 ± 0.19
X61123 BTG1 Negative regulation of cell proliferation 1.60 ± 0.28
L13689 BMI1 Modifies chromatin 0.67 ± 0.09
U67369 GFI1 G1/S-specific transcription in mitotic cell cycle 0.54 ± 0.06
U22376 c-Myb Cell cycle control 0.30 ± 0.10
G2
U66838 CCNA1 Regulation of CDK activity 0.60 ± 0.12
Z36714 CCNF Regulation of cell cycle 0.60 ± 0.11
J04088    0.57 ± 0.14
L47276 TOP2A b Spindle assembly, chromsome condensation 0.42 ± 0.07
X05360 CDC2 Start control point of mitotic cell cycle 0.57 ± 0.11
U28386 KPNA2 Cytoskeleton organization and biogenesis 0.51 ± 0.05
D14678 KIFC1 Spindle assembly, chromsome condensation 0.44 ± 0.10
U14518 CENPA Chromosome organization and biogenesis 0.38 ± 0.06
G2/M
U48807 DUSP4 Regulation of cell cycle 1.40 ± 0.35
U63743 KIF2C Microtubule motor activity 0.72 ± 0.10
U83115 AIM1 Tumor supressor, cytoskeleton 0.71 ± 0.07
M34458 LMNB1 Cytoskeletal anchoring 0.66 ± 0.16
D63880 CNAP1 Mitotic surveilance 0.63 ± 0.05
X65550 MKI67 Chromatin/chromosome structure 0.61 ± 0.09
S78187 CDC25B Cell cycle control 0.60 ± 0.05
D38553 BRRN1 Chromatid separation 0.59 ± 0.08
U73379 UBE2C Protein degradation 0.54 ± 0.08
U30872 CENPF Mitosis 0.53 ± 0.07
Z15005 CENPE Mitotic chromosome movement 0.53 ± 0.10
U29343 HMMR Mitotic surveilance, cell motility 0.51 ± 0.11
U05340 CDC20 Ubiquitin-dependent protein degradation 0.49 ± 0.07
M86699 TTK Spindle assembly/mitotic checkpoint 0.47 ± 0.05
U01038 PLK Mitosis 0.44 ± 0.04
M25753 CCNB1 Mitotic checkpoint 0.43 ± 0.07
D38751 KIF22 Mitosis 0.40 ± 0.18
U04810 TROAP Cell adhesion 0.24 ± 0.03
  1. a Fold change comparing glutathione (GSH) to S-nitrosoglutathione (GSNO)-treated cells, expressed as the mean ± SE (N = 7)
  2. b Represented by more than one probe set on the microarray that reached statistical significance; each result is shown