Figure 3

Phylogenetic relationships and expression profiles in PADs family. This is a fusion tree of three methods (Neighbor joining, maximum parsimony and maximum likelihood). Bootstrap values are calculated for these three methods. Branches length is correlated to sequence evolution rate. Branches lengths between PAD-6 paralogy group members are longer than between PAD-2 paralogy group members. Numbers in small squares correspond to different adult tissues: 1/bone, 2/brain, 3/colon, 4/eye, 5/kidney, 6/liver, 7/lung, 8/mammary gland, 9/pancreas, 10/placenta, 11/skin, 12/thymus, 13/uterus 14/ovary, 15/inner ear, 16/olfactory tissue. Grey squares indicate the presence of expression in the corresponding tissue in updated analysis (January 2005). White squares indicate no expression has been found in this tissue. Red circles indicate duplication.