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Table 2 A list of selected probe measures

From: A class of models for analyzing GeneChip® gene expression analysis array data

Scenario

Calculation

Annotation

1. MAS4.0-equivalent

Z jik = (yji 1k- yji 0k)

Direct difference between PM and MM

2. MAS5.0-equivalent

Z jik = (yji 1k- )

is the Idealized Mis-match (IM)

3. PM only

Z jik = yji 1k

Ignore MM

4. RMA-equivalent

Z jik = log(yji 1k- )

is the mean background estimated from PM for the kth chip

5. Log ratio

Z jik = ln(yji 1k/ yji 0k)

Difference on the logarithmic scale

6. Log difference

Z jik = ln(yji 1k- )

Difference on the logarithmic scale

7. Log PM

Z jik = ln(yji 1k)

PM only on the logarithmic scale

8. Box-Cox on PM

Z jik = ( - 1) / ω

Box-Cox transformation on PM only

9. Box-Cox on PM-IM

Z jik = [(yji 1k- )ω- 1] / ω

Box-Cox transformation on PM-IM