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Table 2 Conserved Cytoplasmic Dynein Subunits in Apicomplexans

From: Comparative genome analysis reveals a conserved family of actin-like proteins in apicomplexan parasites

   Toxoplasma gondll(Tg) Plasmodium falciparum(Pf) Cryptosporidium parvum(Cp) Thelleria parva(Tp)
Dynein Subunit Pfam ID Tg Candidatea Top Matchb E -value c Pfam Scored Pf Candidatea Top Matchb E -value c Pfam Scored Cp Candidatea Top Matchb E -value c Pfam Scored Tp Candidatea Top Matchb E -valuec Pfam Scored
Heavy Chain pfam03028 TgTwinScan_0436 Rn heavy chain 0 402 CAD51040 Rn heavy chain 0 297 EAK88498 Dm heavy chain 0 274 CAI73268 e, f Ce heavy chain 2.00 × 10 -76 76.1
Light Chain pfam01221 TgTwinScan_2634 Mm light chain2 6.00 × 10 -24 148 AAN36221 Rn light chain 1.00 × 10 -38 130 EAL37552 g, h Dm light chain 1 4.00 × 10 -41 142 EAN33478 Rn light chain 2.00 × 10 -27 111
Intermediate Chain nd TgTwinScan_1768 Xt intermediate chain 7.00 × 10 -80   AAN35394 Dd intermediate chain 1.00 × 10 -82   EAK88439 Xt intermediate chain 1.00 × 10 -48   - - - -
Intermediate Light Chain pfam05783 TgTwinScan_4175 Hs intermediate light chain 8.00 × 10 -07 63.9 CAD51749 Gg intermediate light chain 3.00 × 10 -10 72 EAK88297 Gg intermediate light chain 0.023 43.5 - - - -
Dynein Light Chain TcTex1 pfam03645 TgTwinScan_1459 Hs TcTex1 2.00 × 10 -12 81 CAD51956 Hs TcTex1 1.00 × 10-12 70.3 EAK87898 Mm TcTex1 9.00 × 10 -17 83.4 - - - -
Roadblock pfam03259 TgTwinScan_6940 Ci roadblock 6.00 × 10 -34 81.8 AAN35393 Ci roadbloack 1.00 × 10 -24 85.3 EAK88245 Ci roadblock 0.24 - - - - -
  1. nd = not defined
  2. (-) = no significant match
  3. a = gene candidates identified by text and BLASTP searches of http://www.ToxoDB.org, http://www.PlasmoDB.org, http://www.CryptoDB.org, and the NCBI nr database
  4. b = identifying protein found in reciprocal BLASTP search of the NCBI nr database using apicomplexan candidates as query
  5. c = E -value of reciprocal BLASTP search
  6. d = Pfam score as determined by BLASTP comparison to the CDD NCBI database
  7. e = Theileria annulata
  8. f = Tp ortholog EAN34073
  9. g = Cryptosporidium hominis
  10. h = Cp ortholog encoded on contig_AAEE01000005 nt#75605–75871frame1. Translated using GENESCAN webserver
  11. Ce = Caenorhabditis elegans, Ci = Ciona intestinalis, Dd = Dictyostelium discoideum, Dm = Drosophila melanogaster, Hs = Homo sapien, Gg = Gallus gallus, Mm = Mus musculus, Rn = Rattus norvegicus, Xt = Xenopus tropicalis