Significant gene enrichment profiling. The proportions of stress responsive gene probes influenced by diamide (D), H2O2 (H) and menadione (M) treatments are shown in each physiological function category in Part A. The ratios of GSH/GSSG, peroxide and superoxide responsive gene probes calculated for each physiological function category are presented in Part B. Gene probes influenced by dimide, H2O2, menadione treatments in the same way, or by H2O2 and menadione but not by diamide or solely responsive to menadione were regarded as GSH/GSSG, O22- or O2•--responsive, respectively. Symbols ⊕ and indicate significant overrepresentation and underrepresentation of stress-responsive gene probes, respectively, in separate physiological function categories. p values and significant enrichments recorded in sets of gene probes not responding to oxidative stress triggered by diamide, H2O2 and menadione treatments are presented in Additional file 4:Supplement4 for the results of significant enrichment calculations.