Figure 3From: The domain architecture of large guanine nucleotide exchange factors for the small GTP-binding protein ArfThe conserved domains of the BIG/GBF subfamily: DCB domain. Multiple sequence alignement of the conserved domains from BIG and GBF representative sequences showing secondary structure predictions that co-align in all sequences. Colour coding is red for invariant residues, yellow for a sequence similarity score threshold of 0.15 using the BLOSUM62 matrix. The gap in helix 4 is due to an insert in the drosophila Q9V696 sequence, and may be resulting from a sequence annotation error.Back to article page