Textual multiple alignment view. Multiple alignment as rendered by CLUSTAL X. The largest multiple alignment was retrieved from the JAVA applet by a cut and paste operation and rendered in CLUSTAL X . Conserved binding sites are highlighted by red or blue boxes. Known sites as given in TRANSFAC are marked with a dollar sign . Note that the validated Egr-1 site is only conserved in mammals. This site is bound by the serum-inducible Krox-24 zinc finger protein.