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Figure 6 | BMC Genomics

Figure 6

From: Secondary structure in the target as a confounding factor in synthetic oligomer microarray design

Figure 6

Structure in a binding site – full length target and sheared fragments. The position of a 70mer oligonucleotide probe (green) binding site (red dots) within a full-length optimal transcript structure, as well as examples of stable structure in 200mer and 100mer fragments which overlap the probe binding site. Corresponding ΔG values for these fragments modeled at 42° and 52°C are shown in Table 1.

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