Table 3 Summary of G-protein signaling genes in unc-4:: GFP neurons. Genes either known to function in C. elegans motor neuron G-protein signaling pathways or likely to have a role therein (e.g. SER-4) are listed here with KOG descriptions. Transcripts are listed as either enriched with statistical rank (top) or as EGs (bottom).
From: A gene expression fingerprint of C. elegans embryonic motor neurons
Cosmid Name | Common Name | Statistical Rank | KOG Description |
|---|---|---|---|
Enriched | Â | Â | Â |
F47D12.1 | gar-2 | 245 | 7 transmembrane receptor |
Y40H4A.1 | gar-3 | 421 | Muscarinic acetylcholine receptor |
F15A8.5d | dop-1 | 683 | 7 transmembrane receptor |
Y22D7AR.13 | ser-4 | 680 | 7 transmembrane receptor |
Y41G9A.4 | Â | 769 | GABA-B ion channel receptor subunit GABABR1 and related subunits, G-protein coupled receptor superfamily |
M01D7.7a | egl-30 | 124 | G protein subunit Galphaq/Galphay, small G protein superfamily |
F28C1.2 | egl-10 | 872 | G protein signaling regulators |
F57F5.5 | pkc-1 | 743 | Serine/threonine protein kinase |
F17C8.1 | acy-1 | 884 | Adenylyl cyclase |
R07E4.6 | kin-2 | 467 | cAMP-dependent protein kinase types I and II, regulatory subunit |
Present (EGs) | Â | Â | Â |
Y69A2AR.1 | ric-8 | Â | Signaling protein RIC-8/synembryn (regulates neurotransmitter secretion) |
C16C2.2a | eat-16 | Â | G protein signaling regulators |
B0348.4a | egl-8 | Â | Phospholipase C |
F52A8.2 | gpb-2 | Â | G-protein beta subunit |
C26C6.2 | goa-1 | Â | G-protein alpha subunit (small G protein superfamily) |
ZK542.2a | unc-13 | Â | Neurotransmitter release regulator, UNC-13 |
C09E10.2a | dgk-1 | Â | Diacylglycerol kinase |
R06A10.2 | gsa-1 | Â | G protein subunit Galphas, small G protein superfamily |