Table 3 The hypergeometric tests for the partition effect of the deacetylation sites for the co-regulated (YPD) gene pairs. For every correlation threshold, the number of pair-wise correlations for the genes with a common regulator and in the same partition group that are above the threshold was counted. The number of pair-wise correlations for the genes with same regulator and in the neighboring partition groups that are above the threshold was also counted. The probability of randomly drawing such high numbers of gene pairs above the threshold from all of the gene pairs with same regulator is determined by a hypergeometric distribution. The p-values are indicated in the table.
Total gene pairs sharing one regulator | Gene pairs sharing one regulator and both are in the same deacetylation partition group | Threshold for correlations | Number of gene pairs sharing one regulator above the threshold | Number of gene pairs sharing one regulator and both are in the same deacetylation partition group above the threshold | P-values based on the hypergeometric tests |
|---|---|---|---|---|---|
24,833 | 141 | 0.5 | 4,676 | 80 | 3.43e-011 |
| Â | Â | 0.6 | 2,925 | 54 | 2.37e-011 |
| Â | Â | 0.7 | 1,519 | 45 | 2.24e-011 |
| Â | Â | 0.8 | 422 | 20 | 2.92e-011 |
| Â | Â | 0.9 | 30 | 3 | 0.0000243 |
Total gene pairs sharing one regulator | Gene pairs sharing one regulator and they belong to neighboring deacetylation partition groups | Threshold for correlations | Number of gene pairs sharing one regulator above the threshold | Number of gene pairs sharing one regulator and they belong to neighboring deacetylation partition groups above the threshold | P-values based on the hypergeometric tests |
24,833 | 46 | 0.5 | 4,676 | 12 | 0.0784 |
| Â | Â | 0.6 | 2,925 | 8 | 0.0853 |
| Â | Â | 0.7 | 1,519 | 8 | 0.00165 |
| Â | Â | 0.8 | 422 | 2 | 0.0432 |
| Â | Â | 0.9 | 30 | 0 | 0.0541 |