Karyoscope views of S288C-S288C and S. bayanus -S288C microarray hybridizations. Microarray hybridizations were performed as described in the text. In both panels the S. cerevisiae laboratory strain S288C was used as a reference sample, labeled with Cy3 dye (green). In panel A, the Cy5-labeled (red) DNA was also S288C, giving a self-self hybridization. In panel B, the Cy-5 labeled DNA was S. bayanus. The labeled DNAs were competitively hybridized to spotted microarrays bearing full-length ORFs from the S288C S. cerevisiae strain; the data thus obtained is displayed here in graphical form as a karyoscope. Red bars indicate red:green ratios above 1.0 and are graphed on a log scale; green bars indicate red:green ratios below 1.0, also graphed on a log scale. The chromosomes are shown in each panel in numerical order with chromosome 1 at the top and chromosome 16 at the bottom, and are aligned by their centromeres, with their left arms extending to the left. Both karyoscopes are drawn to the same scale, i.e., the bar heights in panels A and B proportionally represent the same amplitude of change.