From: Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals
I: Expected cases | ||
---|---|---|
Number | Function / expression | Transcription factors |
4 | lymphocytes | Irf1/Irf2/ISRE, NFKB [34-36] |
6 | liver | HNF-1 alpha and beta, HNF4 alpha [32, 59-61] |
9,12 | cardiac and skeletal muscle | MyoD/E47, MEF2 family factors, SRF [4, 6, 48] |
15 | erythroid cells | GATA-1 [62] |
16 | B lymphocytes | Spi-B, Oct-I* [37, 40, 63] |
22 | cell cycle | E2F family factors [49, 50] |
40 | smooth muscle | SRF [5, 64] |
II: Extended | ||
3 | neural tissue | NRSF [65] |
5 | testis | SOX17, RFX2 (RFX1-RFX3) [41-43] |
6 | liver | ARP-1/COUP-TF, PPARγ [66, 67] |
13 | ER | XBP-1 [68] |
15,16 | erythroid cells/ B cells | AREB6* [38] |
17 | kidney | HNF-4alpha, HNF-1-alpha/beta [69, 70] |
III: Unexpected | ||
1 | protein synthesis | NRF and ETS family factors |
2 | oocyte | E2F and ETS family factors |
6 | liver | ROR-alpha |
8 | ECM | Pax4 |
9 | cardiac muscle | TALE family factors TGIF and MEIS1 |
13 | ER | NRF and ETS family factors |
24 | pancreas | E47 |
30 | small intestine | HNF4-alpha and GATA factors |
44 | retina/eye | Ik-2 |
45 | testis | cap |