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Table 3 Differently regulated (p ≤ 0.05) non-SLC transporters with a minimum absolute fold change of four in any pair-wise comparison of adjoining intestinal segments. Bold cases indicate fold changes of five or higher (Means ± SDs, log2 scale, n = 3 or 9, respectively.).

From: Changes in the transcriptional profile of transporters in the intestine along the anterior-posterior and crypt-villus axes

Gene Name D>J D<J J>I J<I I>C I<C SI>C SI<C Literaturea Gene aliases References
Aldh9a1      2.4 ± 0.1     - ESTM40; TMABA-DH -
Apoc2    3.7 ± 0.5   2.5 ± 0.5   4.9 ± 0.6   Mouse: expressed in intestine; Rabbit: expressed in J, D; Human: expressed in J - [87-89]
Aqp4       4.6 ± 0.8   4.3 ± 0.3 Mouse: present in SI in crypt cells, and C in epithelial surface cells; rat: SI, C MIWC; mMIWC [90, 91]
Aqp5 2.9 ± 0.4         Rat: D only - [91]
Aqp8       4.8 ± 0.6   3.9 ± 0.4 Rat: SI and C - [91]
Atp2a3         2.1 ± 0.2 Human: C > SI Serca3; SERCA3b [92]
Atp7a 2.5 ± 0.5    4.0 ± 0.4      Human: Highly expressed in D Mo; br; Blo; I14; blotchy; mottled; MNK; brindled [93]
Chrna1 2.5 ± 0.4         - Acra; Achr-1 -
Chrne      2.0 ± 0.4     - Acre -
Csng      2.0 ± 0.8     - Csn1s2a; Csn1s2b -
D11Ertd18e    4.7 ± 0.5     4.7 ± 1.0   - - -
Fabp1    5.2 ± 1.1   4.7 ± 1.1   8.3 ± 0.10   Mouse: D, proximal J>I, nothing in distal I; Human: highest in J, present in D, J, I, C Fabpl; L-FABP [94]
Gfpt1     2.2 ± 0.4     2.4 ± 0.4 Mouse: expressed in SI and C; Human: C > SI GFA; GFAT; Gfpt; GFAT1 [95, 96]
Gfpt2        2.1 ± 0.4   Human: SI and C very low expressed - [96]
Gria1 2.2 ± 0.5         - Glr1; Glr-1; GluRA; Glur1; HIPA1; GluR-A; Glur-1 -
Grm3       2.4 ± 1.2   2.3 ± 1.2 - Gprc1c; mGluR3 -
Gsr     2.1 ± 0.3      - Gr1; Gr-1 -
Kcna3    2.9 ± 0.6      2.0 ± 0.4 - Mk-3; Kv1.3; Kca1-3 -
Kcnk6          Mouse: C > SI Toss; Twik2; [97]
Kctd3   2.7 ± 1.2 2.7 ± 1.3       - NY-REN-45 -
Pkd2         2.4 ± 0.5 - - -
Pln         2.6 ± 0.5 - PLB -
Rbp2    2.8 ± 0.2   3.0 ± 0.3   4.7 ± 0.5   - Rbp-2; Crbp-2; CrbpII -
Rbp7      2.9 ± 0.3   2.7 ± 0.3   - CRBP-III -
Saa3       3.5 ± 0.6   4.0 ± 0.4 Mouse and Human: Expressed in SI and C Saa-3 [98]
Stard5       2.9 ± 1.0    - D7Ertd152e -
Stx1b1      3.0 ± 1.2     - Stx1bl -
Trpm7     2.0 ± 1.0      - CHAK; PLIK CHAK1; Ltpr7; Ltrpc7; -
Xdh        2.8 ± 0.3   Mouse: Strong in SI Xor; Xox1; Xox-1 [99]
  1. aD = Duodenum, J = Jejunum, I = Ileum, C = Colon, SI = Small intestine, - = No data found in the literature