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Figure 4 | BMC Genomics

Figure 4

From: A new approach for the analysis of bacterial microarray-based Comparative Genomic Hybridization: insights from an empirical study

Figure 4

Log Ratio distribution of genes absent from strain RM1221. We plotted the LR distribution of genes predicted to be absent from strain RM1221 based on BLAST searches of NCTC 11168 against the RM1221 genome. Because of the lack of Tester signal predicted from these genes, LRs should be expected to be highly negative. The LR distribution (A) appeared to be bimodal with a significant number of genes bearing unusually high LRs. Further examination of these genes revealed a potential bias towards genes represented by short probes on the microarray (i.e. less than 250 bp). Separate re-plotting of the LR distributions of long (B) and short (C) probes confirms a higher average LR among genes with short probes.

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BMC Genomics

ISSN: 1471-2164

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