Table 1 The 53 most divergent (>2 SD) genes in H. pylori strain J99 by DNS showing their ranking in strain 26695 and in TNS and HNS analysis
DNS order | JHP # | annotation | 26695 # | 26695 DNS order | TNS order | HNS order |
|---|---|---|---|---|---|---|
1 | JHP0952 | hypothetical protein | HP0427 | 14 | 3 | 1355 |
2 | JHP0476 | cag pathogenicity island protein (cag7) | HP0527 | 1 | 2 | 2 |
3 | JHP0556 | vacuolating cytotoxin (vacA) paralog | HP0609/10 | 4/13 | 5 | 4 |
4 | JHP0274 | vacuolating cytotoxin (vacA) paralog | HP0289 | 2 | 6 | 5 |
5 | JHP0305 | hypothetical protein | HP0322 | 3 | 8 | 10 |
6 | JHP0942 | hypothetical protein | HP0996 | 5 | 13 | 27 |
7 | JHP0856 | vacuolating cytotoxin (vacA) paralog | HP0922 | 6 | 9 | 6 |
8 | JHP0050 | hypothetical protein | HP0058 | 88 | 7 | 84 |
9 | JHP1300 | hypothetical protein | HP1408 | 15 | 1 | 1 |
10 | JHP1044 | hypothetical protein | HP1116 | 8 | 14 | 8 |
11 | JHP0928 | hypothetical protein | NAH | - | 12 | 9 |
12 | JHP0074 | hypothetical protein | HP0080 | 9 | 32 | 125 |
13 | JHP0440 | hypothetical protein | HP0488 | 7 | 16 | 17 |
14 | JHP1042 | hypothetical protein | HP1115 | 20 | 25 | 694 |
15 | JHP1321 | histidine and glutamine-rich metal-binding protein | HP1432 | 46 | 4 | 49 |
16 | JHP0934 | hypothetical protein | NAH | - | 15 | 95 |
17 | JHP0495 | cag island protein (cagA) | HP0547 | 31 | 20 | 12 |
18 | JHP0931 | topoisomerase I (topA 3) | NAH | - | 18 | 20 |
19 | JHP0693 | hypothetical protein | HP0756 | 24 | 59 | 1490 |
20 | JHP0632 | N-methylhydantoinase | HP0696 | 19 | 44 | 36 |
21 | JHP0471 | cag pathogenicity island protein (cag3) | HP0522 | 11 | 35 | 62 |
22 | JHP0438 | outer membrane protein | HP0486 | 26 | 67 | 145 |
23 | JHP0026 | hypothetical protein | HP0030 | 45 | 36 | 64 |
24 | JHP1084 | outer membrane protein (omp26) | HP1157 | 34 | 17 | 24 |
25 | JHP0481 | cag island protein (cagT) | HP0532 | 23 | 70 | 558 |
26 | JHP0052 | hypothetical protein | HP0059 | 43 | 24 | 120 |
27 | JHP0336 | hypothetical protein | HP1089 | 12 | 51 | 54 |
28 | JHP1426 | iron(III) dicitrate transport protein (fecA) | HP1400 | 32 | 78 | 111 |
29 | JHP0174 | hypothetical protein | HP0187 / 8 / 6 | 47&1127&596 | 88 | 90 |
30 | JHP1297 | type III restriction enzyme (res) | NAH | - | 63 | 28 |
31 | JHP0953 | hypothetical protein | NAH | - | 26 | 1463 |
32 | JHP0067 | urease beta subunit (urea amidohydrolase) (ureB) | HP0072 | 21 | 37 | 70 |
33 | JHP0941 | integrase/recombinase (xerD) | HP0995 | 25 | 100 | 541 |
34 | JHP0548 | flagellin A (flaA) | HP0601 | 33 | 40 | 154 |
35 | JHP0299 | hypothetical protein | HP061/2 | 230&765 | 11 | 275 |
36 | JHP1033 | hypothetical protein | HP1106 | 59 | 262 | 342 |
37 | JHP1409 | type II restriction enzyme (methyltransferase) | NAH | - | 55 | 15 |
38 | JHP0626 | iron(III) dicitrate transport protein (fecA) | HP0686 | 62 | 89 | 47 |
39 | JHP0940 | hypothetical protein | NAH | - | 53 | 393 |
40 | JHP1253 | hypothetical protein | HP1333 | 40 | 75 | 384 |
41 | JHP0132 | cytochrome oxidase (cbb3 type) (fixN) | HP0144 | 27 | 206 | 209 |
42 | JHP0842 | hypothetical protein | HP0906 | 42 | 29 | 21 |
43 | JHP0925 | hypothetical protein | NAH | - | 130 | 990 |
44 | JHP0613 | hypothetical protein | HP0669 | 69 | 42 | 33 |
45 | JHP0565 | DNA mismatch repair protein (mutS) | HP0621 | 22 | 227 | 82 |
46 | JHP1363 | DNA polymerase I (polA) | HP1470 | 30 | 81 | 46 |
47 | JHP0489 | cag island protein (cagH) | HP0541 | 71 | 137 | 398 |
48 | JHP1260 | siderophore-mediated iron transport protein (tonB) | HP1341 | 85 | 1260 | 402 |
49 | JHP0492 | DNA transfer protein (cagE) | HP0544 | 104 | 95 | 50 |
50 | JHP1121 | DNA-directed RNA polymerase, beta subunit (rpoB) | HP1198 | 84 | 23 | 16 |
51 | JHP1434 | DNA repair protein (recN) | HP1393 | 35 | 177 | 160 |
52 | JHP0491 | cag island protein (cagF) | HP0543 | 82 | 170 | 828 |
53 | JHP0191 | hypothetical protein | HP0205 | 57 | 33 | 7 |