Figure 3
From: Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11
FISH analysis of BAC clones RP11-573E11 (panel A), RP11-51B23 and RP11-47J17 (not shown) in parental cells NGP.1A.TR1 (with a derivative chromosome 11, due to an unbalanced translocation between chromosomes 11 and 2) confirms the existence of a small deletion in 11p15.3. The breakpoint of the distal 11q25->11qter deletion of the transferred chromosome in subclone MCH574c3 was mapped between BAC clones RP11-340L13 (not shown) and RP11-697E14 (panel B).