Genome-wide isolation of growth and obesity QTL using mouse speed congenic strains

BMC Genomics

Table 5 Adiposity phenotypes of HG.CAST speed congenic strains

Strain	Sex	N	GFP (g)	FFP (g)	MFP (g)	RFP (g)	TF (g)	AI (%)	BMI
HGC	M	31	0.477 ± 0.020	0.317 ± 0.011	0.298 ± 0.010	0.110 ± 0.006	1.202 ± 0.042	3.3 ± 0.1	35.0 ± 0.3
HG1	M	19	0.473 ± 0.029	0.353 ± 0.016	0.258 ± 0.014	0.106 ± 0.009	1.190 ± 0.061	3.5 ± 0.2	35.2 ± 0.5
HG8	M	15	0.418 ± 0.038	0.340 ± 0.021	0.230 ± 0.018	0.099 ± 0.012	1.087 ± 0.080	3.0 ± 0.2	33.8 ± 0.6
HG9	M	29	0.615 ± 0.021	0.453 ± 0.012	0.283 ± 0.010	0.166 ± 0.007	1.518 ± 0.045	4.3 ± 0.1	35.6 ± 0.4
HG11	M	23	0.516 ± 0.027	0.312 ± 0.015	0.281 ± 0.013	0.120 ± 0.009	1.229 ± 0.058	3.2 ± 0.2	35.5 ± 0.5
HG17	M	10	0.540 ± 0.043	0.344 ± 0.024	0.278 ± 0.021	0.124 ± 0.014	1.285 ± 0.091	3.8 ± 0.3	35.1 ± 0.8
HGC	F	23	0.370 ± 0.023	0.305 ± 0.013	0.269 ± 0.011	0.076 ± 0.007	1.020 ± 0.048	3.9 ± 0.1	28.1 ± 0.4
HG1	F	31	0.336 ± 0.025	0.328 ± 0.14	0.205 ± 0.012	0.055 ± 0.008	0.924 ± 0.053	3.8 ± 0.2	27.9 ± 0.4
HG8	F	22	0.247 ± 0.037	0.310 ± 0.021	0.193 ± 0.018	0.043 ± 0.012	0.793 ± 0.079	3.1 ± 0.2	27.8 ± 0.6
HG9	F	27	0.624 ± 0.021	0.518 ± 0.012	0.288 ± 0.010	0.152 ± 0.007	1.581 ± 0.045	6.1 ± 0.1	29.9 ± 0.4
HG11	F	24	0.436 ± 0.024	0.332 ± 0.014	0.269 ± 0.012	0.087 ± 0.008	1.124 ± 0.052	4.5 ± 0.2	28.5 ± 0.4
HG17	F	17	0.410 ± 0.029	0.350 ± 0.016	0.262 ± 0.014	0.086 ± 0.009	1.107 ± 0.062	4.4 ± 0.2	28.9 ± 0.5

GFP, gonadal fat pad; FFP, femoral fat pad; MFP, mesenteric fat pad; RFP, retroperitoneal fat pad; TF, summed weight of four fat pads; AI, adiposity index (TF/body weight*100) and BMI, body mass index (body weight at sacrifice/NA² *100). Values are expressed as least square means (LSMEANS) ± SEM. LSMEANS in bold are significantly different than the control (HGC) (critical P < 0.005) after Bonferroni correction within each sex.

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