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Table 4 Summary of interaction strengths

From: Direct and heterologous approaches to identify the LET-756/FGF interactome

Interactors Y2H- screen Co-IP Coloc Deloc Class
RPS-16 ++ ++ + + I
FTT-1 ++ +++ - + I
FTT-2 ++ +++ - + I
KIN-10 ++ + + + I
PAL-1 +++ + + + I
C15C6.2 ++ ++ + - II
RPL-6 ++ ++ - + II
DAF-21 + ++ ND III
COL-129 ++ + + - III
SKR-2 ++ ++ ND III
KIN-3 + ++ +/- - III
C18A3.3 + ++ ND III
  1. Scores obtained in the different assays used: (i) two-hybrid assays, (ii) co-immunoprecipitation (co-IP), (iii) colocalization by immunofluorescence in single transfected cells (Coloc) and (iv) delocalization (Deloc) of one or the two partners induced by the cotranfection. Interactions were classified as I (the strongest) to III (the weakest).