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Table 3 Non-synonymous substitutions significant group (p < 0.10) of Orthologs with SNP Pairs potential involves in pathogenicity

From: Conserved genes in a path from commensalism to pathogenicity: comparative phylogenetic profiles of Staphylococcus epidermidis RP62A and ATCC12228

S. epidermidis ATCC12228

S. epidermidis RP62A

Function

N

S

dN/(dS+ dN)

p value

  

Annotation from ATCC12228

New annotation

    

SE1029

SERP0918

exonuclease SbcC

 

5

0

1.0000

0.0107

SE0231

SERP2349

fosfomycin resistance protein fofB

 

4

0

1.0000

0.0228

SE0800

SERP0689

potD protein

 

3

0

1.0000

0.0381

SE0265

SERP2313

hypothetical protein

Tranmembrane protein

3

0

1.0000

0.0383

SE1546

SERP1399

D-3-phosphoglycerate dehydrogenase

 

3

0

1.0000

0.0392

SE0378

SERP0259

hypothetical protein

Tranmembrane protein

3

0

1.0000

0.0398

SE2085

SERP2099

gluconokinase

 

3

0

1.0000

0.0401

SE1042

SERP0931

peptide methionine sulfoxide reductase

 

3

0

1.0000

0.0405

SE0039

SERP2495

conserved hypothetical protein

 

3

0

1.0000

0.0406

SE0977

SERP0866

glycerol uptake facilitator

 

3

0

1.0000

0.0415

SE1170

SERP1049

probable ATP-dependent DNA helicase RecQ

 

3

0

1.0000

0.0425

SE0502

SERP0385

choline transport ATP-binding protein

 

3

0

1.0000

0.0427

SE0546

SERP0431

conserved hypothetical protein

YvcD

3

0

1.0000

0.0440

SE1302

SERP1183

deoxyribonuclease

 

2

0

1.0000

0.0668

SE1527

SERP1382

conserved hypothetical protein

YheB (surface protein)

2

0

1.0000

0.0707

SE2166

SERP2177

glycine betaine aldehyde dehydrogenase gbsA

 

2

0

1.0000

0.0719

SE2379

SERP0037

cystathionine gamma-synthase

 

2

0

1.0000

0.0743

SE1828

SERP1836

DNA topoisomerase III topB

 

2

0

1.0000

0.0743

SE1824

SERP1831

50S ribosomal protein L3

 

2

0

1.0000

0.0759

SE0309

SERP0186

30S ribosomal protein S12

 

2

0

1.0000

0.0766

SE0463

SERP0349

putative deoxyribodipyrimidine photolyase

 

2

0

1.0000

0.0766

SE2067

SERP2080

glycine betaine aldehyde dehydrogenase gbsA

 

2

0

1.0000

0.0766

SE2215

SERP2247

arginine/oirnithine antiporter

 

2

0

1.0000

0.0766

SE0806

SERP0695

conserved hypothetical protein

YlaF

2

0

1.0000

0.0768

SE1448

SERP1335

conserved hypothetical protein

YqgE (MultiDrug Efflux proteins)

2

0

1.0000

0.0775

SE0847

SERP0737

hypothetical protein

phenol soluble modulin beta 1

2

0

1.0000

0.0777

SE0790

SERP0679

conserved hypothetical protein

YkyA (surface protein)

2

0

1.0000

0.0779

SE2196

SERP2207

conserved hypothetical protein

 

2

0

1.0000

0.0781

SE2269

SERP0153

dihydropteroate synthase chain A synthetase

 

2

0

1.0000

0.0783

SE0744

SERP0630

2-oxoglutarate decarboxylase

 

2

0

1.0000

0.0783

SE2003

SERP2016

conserved hypothetical protein

 

2

0

1.0000

0.0783

SE1247

SERP1126

conserved hypothetical protein

YqfN

2

0

1.0000

0.0787

SE1986

SERP1998

conserved hypothetical protein

In larger Bacterial clades

2

0

1.0000

0.0800

SE0432

SERP0317

low-affinity inorganic phosphate transporter

 

2

0

1.0000

0.0808

SE1745

SERP1754

conserved hypothetical protein

YhfK

2

0

1.0000

0.0827

SE0674

SERP0564

clpB protein

 

2

0

1.0000

0.0846

SE0773

SERP0660

conserved hypothetical protein

Cation transporter

2

0

1.0000

0.0846

SE1608

SERP1461

beta-lactamase

 

2

0

1.0000

0.0846

SE2128

SERP2140

conserved hypothetical protein

YfmM

2

0

1.0000

0.0874

SE0506

SERP0389

alcohol dehydrogenase

 

7

1

0.7451

0.0953

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BMC Genomics

ISSN: 1471-2164

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