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Table 2 Expression of ASS, CHL1, and FLAP in 2 sets of discordant monozygotic twins relative to expression levels in their respective normal siblings

From: Gene expression profiling of lymphoblastoid cell lines from monozygotic twins discordant in severity of autism reveals differential regulation of neurologically relevant genes

Gene name Genbank # A1 M1 A2 M2
ASS AA676405 0.65 (0.81)* -0.13 (0.27) 1.77 (3.04) 0.18 (0.97)
CHL1 H15267 1.60 (1.64) 0.67 (1.39) 1.15 (0.78) 0.95 (0.60)
FLAP T49652 0.71 (1.10) 0.13 (0.77) 1.40 (1.45) -0.09 (-0.39)
  1. Values are mean log2(ratio) measures of gene expression between a twin and his respective normal sibling, obtained by DNA microarray analyses with dye reversal replicates
  2. * Values in parentheses are mean log2(ratio) measures obtained by triplicate qPCR analyses.
  3. A = autistic twin as diagnosed by ADI-R scoresheet
  4. M = more mildly affected twin who did not meet ADI-R criteria for autism
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