Table 1 Statistics of single domains. Domains in the underlying interaction network are characterized according to their degree k and their strength s, defined as the sum of all weights the domain in question is involved in. Here, we show the 10 most connected and strongest PFAM domains.
PFAM domain | description | degree k | PFAM domain | description | strength s |
|---|---|---|---|---|---|
PF01423 | LSM | 72 | PF01423 | LSM | 777.7 |
PF00071 | ras | 50 | PF00118 | TCP-1/cpn60 | 294.5 |
PF00022 | actin | 50 | PF00022 | actin | 291.5 |
PF00069 | pkinase | 49 | PF00069 | pkinase | 289.0 |
PF00076 | rrm1 | 45 | PF00071 | ras | 263.5 |
PF00118 | TCP-1/cpn60 | 43 | PF00076 | rrm1 | 253.4 |
PF00096 | zf-C2H2 | 39 | PB075870 | – | 248.8 |
PB075780 | – | 39 | PF00227 | proteasome | 237.1 |
PF00036 | efhand | 36 | PF01008 | IF-2B | 226.5 |
PF01008 | IF-2B | 35 | PF00001 | 7tm-1 | 226.0 |